CRISPR could use gold nanoparticles to edit your brain
Add this to the list of possible applications for the seemingly-magical gene editing technology CRISPR: helping people with neurological disorders edit their brains with pinpoint accuracy to alleviate the symptoms of their disorder.
That’s the potential promise of a new study, out today in the journal Nature Biomedical Engineering. In the study, a team of researchers from the University of Texas and the University of California at Berkeley as well as a Berkeley-based company called GenEdit describe a new process for using gold nanoparticles for the delivery of the Cas9 enzyme that does the editing. They say this technique, first described in a 2017 paper dealing with gene editing in muscle cells, could pose fewer problems than the viruses that serve as CRISPR’s conventional delivery method. And the new paper offers an almost-unheard of application for CRISPR: editing inside the adult brain.